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Investors are on the hunt for startups that can solve social or environmental problems: In 2022, total assets devoted to “impact investing” topped $1 trillion for the first time. These companies have proved particularly adept at steering investor capital to companies with worldimproving ideas. Anglo-Australian firm LeapFrog Investments focuses on companies that provide financial services, health care, and clean energy to lower-income consumers in Africa and Asia. Its portfolio of 30 companies includes Sun King, whose rooftop solar-energy panels serve more than 100 million people; and HealthifyMe, an app that delivers personalized health advice to customers in more than 300 cities in India and Southeast Asia. TPG Rise, an impact private equity firm, now manages $17 billion—including $7.3 billion in its Rise Climate fund. Rise Climate’s big bets include stakes in Nextracker, whose solar panels move to track the sun across the sky, maximizing their energy yield; Monolith, a big player in the race for green hydrogen; and an EV-and-battery-development partnership with Indian automotive giant Tata Motors. Biotech VC firm Flagship Pioneering, best known for incubating vaccine maker Moderna, has launched more than 100 other companies. Two of them have made particularly big waves in 2023: Seres Therapeutics, whose therapy VOWST was approved by the FDA to treat dangerous recurrent C. difficile infections; and Indigo Ag, which helps farmers earn extra revenue by adopting sustainable agriculture practices and thus earning, and selling, carbon credits.

31.Volvo

GOTHENBURG, SWEDEN

The maker of trucks, buses, and construction equipment is shrinking its carbon footprint by leaning into “green steel”—using metal that’s forged with energy from hydrogen instead of fossil fuels.

32.Grail

MENLO PARK, CALIF.

Early detection and diagnosis can reduce cancer mortality rates by 26%. Grail’s Galleri blood test can detect a shared signal across more than 50 types of cancers, increasing the odds of an early start on treatment.

33.JPMorgan Chase

A rebounding city becomes a springboard for helping entrepreneurs of color.

NEW YORK CITY

In the summer of 2013, Detroit hit economic rock bottom. With the city’s population down more than 60% from its 1950s peak, and the auto industry still reeling from the Great Recession, the city declared bankruptcy; its unemployment rate topped 25%. To help the city bounce back, JPMorgan Chase teamed up with local government and nonprofits on Invested in Detroit, a program through which it has poured over $200 million into Detroit’s economy in the form of job training, loans for small businesses, and real estate financing. The bank’s biggest innovations have involved extending credit to people who lacked the collateral or credit histories to qualify for traditional loans—a major problem in underserved and lower-income communities.

A decade on, the program is making a difference. To date, Invested in Detroit has helped place some 72,000 Detroiters into apprenticeships or jobs, while providing financing or technical aid to 13,000 small businesses. Detroit’s jobless rate is now just 6.4%. JPMorgan Chase, meanwhile, has benefited from a healthier economy: Since 2017, its deposits, commercial lending, and market share in the metro area have all risen substantially. And the bank has taken some of its innovations national and global: Its Entrepreneurs of Color Fund, first launched in Detroit, has now made more than 2,100 loans, worth over $115 million, to entrepreneurs nationwide.

34.Intuition Robotics

A “companion robot” that’s helping socially isolated seniors stay healthy.

RAMAT GAN, ISRAEL

For older people, loneliness can be a threat as real as any disease: Estimated to cost Medicare $7 billion a year, the condition is associated with higher risk of cardiovascular disease, stroke, dementia, anxiety, depression, and premature death. ElliQ, Intuition Robotics’ “companion robot,” aims to address the problem. About the size of a desk lamp, and equipped with a touch screen and empathetic voice-interaction software, the robot can both keep seniors company throughout the day and encourage healthy habits—valuable services at a time when the number of elderly people is growing far faster than the number of caregivers.

New York’s Office for the Aging began piloting ElliQ last year among some 300 socially isolated seniors. Acting director Greg Olsen says that 95% of its users report a reduction in loneliness and an overall improvement in health—thanks to ElliQ’s messaging and activities around hydration, medication, nutrition, cognitive games, and mindfulness.

35.Swatch

BIENNE, SWITZERLAND